ⅠA期肺腺癌临床高危因素及术后辅助治疗研究进展
作者:
作者单位:

1.海南医科大学,海南 海口,570216;2.海南医科大学第二附属医院 胸外科,海南 海口,570216

作者简介:

陈火育,男,硕士研究生,研究方向为肺癌。

通讯作者:

孙伟,男,博士,主任医师,研究方向为肿瘤学。

中图分类号:

R734.2;R730.5

基金项目:


A review on clinical high-risk factors and postoperative adjuvant therapy in stage ⅠA lung adenocarcinoma
Author:
Affiliation:

1.Hainan Medical University, Haikou, 570216, Hainan, China;2.Department of Thoracic Surgery, the Second Affiliated Hospital of Hainan Medical University, Haikou, 570216, Hainan, China

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    摘要:

    现有指南不推荐ⅠA期肺腺癌患者行术后辅助治疗,但伴临床高危因素的ⅠA期肺腺癌患者有较高的复发转移风险,单纯手术治疗可能不足以确保远期疗效。如何及何时开展术后辅助治疗,以改善ⅠA期复发高风险患者的生存,是未来需要去解决的问题。本文将探讨具有临床高危因素(T分期、实性成分占比、高级别病理亚型及百分比、气腔扩散、脉管癌栓等)的ⅠA期肺腺癌复发高危人群预后及术后辅助治疗的研究进展。

    Abstract:

    The existing guidelines do not recommend postoperative adjuvant therapy for patients with stage ⅠA lung adenocarcinoma. However, patients with stage ⅠA lung adenocarcinoma containing clinical high-risk factors have a higher risk of recurrence and metastasis, and surgery alone may not be sufficient to ensure long-term efficacy. How and when to carry out postoperative adjuvant therapy to improve the survival of stage ⅠA patients with high risk of recurrence become a problem that needs to be solved in the future. This article will discuss the research progress of the prognosis and postoperative adjuvant therapy of stage ⅠA lung adenocarcinoma patients with high-risk factors (T stage, consolidation tumor ratio, high-grade pathological subtypes and percentage, spread through air space, lympho-vascular invasion, etc.).

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陈火育,程磊,彭东阁,孙伟.ⅠA期肺腺癌临床高危因素及术后辅助治疗研究进展[J].肿瘤药学,2024,14(6):695-701 ( in Chinese)

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  • 在线发布日期: 2025-02-25
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