Abstract:Objective To investigate the clinical value of general combined epidural anesthesia during operation of esophageal carcinoma. Methods Fifty-eight patients with carcinoma of esophagus were randomly divided into observation group (n=29) and control group (n=29). The observation group had general combined with epidural anesthesia and the control group only had general anesthesia. The mean artery pressure (MAP), heart rate (HR), time of postoperative revival and extubation were recorded and compared. Results The difference of MAP and HR between the two groups had no statistical meaning before anesthesia (H0), but had statistical significance at the time points of H1, H2, H3 and H4 (P<0.05). Patients in observation group took shorter time to get autonomous respiration, extubation and orientation regaining than those in control group (P<0.05). Conclusion General combined epidural anesthesia had good effects during operation of esophageal carcinoma. It could lessen the dose of anaesthetic and render patients take shorter time to get recovery.